The Main Street Family Clinic building and sign in Canton, Oklahoma

Your Primary Care Clinic
in Canton, Oklahoma

Main Street Family Clinic provides personalized, professional family medicine for all ages. From routine checkups to minor procedures, we are here to help you stay healthy and feel your best.

Quality Healthcare For All Ages & Needs

We are able to assess and treat acute and urgent matters as well as manage the more complex issues of people with chronic health problems in a timely and professional manner.

  • A provider caring for a patient in the exam room
  • Wellness Visits for All Ages
  • Sick and Acute Visits
  • Medicare Annual Wellness Visits
  • Weight Loss Management
  • Minor Dermatologic Procedures
  • Toenail Removals
  • Vaccine Administration
  • Laceration Repairs
  • Joint Injections
  • Lab Draws
  • DOT Physicals

If you have a health issue that you would like to discuss with us, please call us at 580-886-1400 or stop by any time. After all, we are family. ¡También se habla español!

Meet The Main Street
Family Team

Born, Raised & Serving
in Northwest Oklahoma

Beth Holderby Acre, Lead Medical Provider and Founder

Lead Medical Provider & Founder

Beth Holderby Acre

APRN-CNP, RN, MSN, BS, ADN

Main Street’s founder with a passion for bringing state-of-the-art healthcare to the citizens of rural Oklahoma.

Joni McDonald, Clinic Manager and Phlebotomist

Clinic Manager & Phlebotomist

Joni McDonald

PBT

The friendly voice of Main Street! Dedicated to care, and a successful business owner for over ten years in Woodward, Oklahoma.

About Beth Holderby Acre, APRN-CNP, RN, MSN, BS, ADN

Lead Medical Provider & Founder

Beth grew up in Alfalfa County as the daughter of a nurse and farmer/rancher. She was taught the value of hard work and perseverance graduating as valedictorian from Timberlake High School. While pursuing a Bachelor of Science degree in Microbiology from Oklahoma State University, she was very active in Kappa Alpha Theta Sorority. Soon after, she moved to Durham, North Carolina where she worked in the healthcare industry and travelled widely, gaining insights into the healthcare of various people.

Shortly thereafter, she returned home to begin nursing school at Northern Oklahoma College. After graduation, she worked in the Intensive Care Unit at St. Mary’s in Enid where she developed a foundation caring for patients with a wide array of medical problems. While employed, she started nurse practitioner school online through the University of South Alabama, graduating in 2013.

Her first position as a Family Nurse Practitioner was at Mercy Division Clinic in Guthrie. Four years later, Beth married Charlie Acre and relocated to Canton establishing a home in Northwest Oklahoma again. She practiced at Great Salt Plains (GSP) Clinic in Canton for almost 6 years where she first started caring for the people of her community and rural area.

Beth continued her treatment of rural Oklahomans at the Okeene Hospital Medical Clinic until opening this clinic in November of 2025. She is thrilled to be providing care for her fellow rural Oklahomans who she considers her friends and family.

Beth Holderby Acre, Lead Medical Provider and Founder

About Joni McDonald, PBT

Clinic Manager & Phlebotomist

As a proud graduate, and valedictorian, of Canton High School, I knew that someday I wanted to return home and raise my children. Immediately following high school, I opened my own business in Woodward, Oklahoma, and successfully operated it for 10 years. I also managed an oilfield industry office, which gave me insight into office efficiency and procedures. Together, these experiences helped me recognize that my calling was interacting with people and the personal satisfaction attained when meeting their needs.

In 2020, I was welcomed into the rural healthcare field and realized working in healthcare and directly caring for patients in my hometown and from surrounding communities was exactly where I needed to be. I cherish working in rural Northwest Oklahoma where I was raised and shaped into the woman I am today.

It is important that I give back to the people who have supported me and my three children. I love what I do and adore taking care of the patients at Main Street Family Clinic. Our patients aren’t just patients to me, they are family.

Joni McDonald, Clinic Manager and Phlebotomist

Insurance & Payment Options

Affordable healthcare for our community is our goal!

Accepted Insurance

Main Street Family Clinic is in network
with many major insurance plans.

Major Insurance Networks

  • Aetna
  • First Health
  • Coventry
  • CIGNA
  • HealthChoice
  • Medicare
  • Medicaid
  • Healthcare Highway
  • United Healthcare
  • PHCS/MultiPlan

Blue Cross Blue Shield of Oklahoma (BCBSOK)

  • BAV - MyBlue
  • BVP - Blue Advantage PPO
  • EPP - Blue Preferred
  • HMO - BlueLincs HMO
  • MCA - Medicare Part D HMO
  • NTV - Native Blue
  • PAR - Blue Traditional
  • PMC - Medicare Part D PPO
  • PPO - Blue Choice PPO
  • SPN - Plan 65 Select

Important: Many insurance companies have multiple plan types. Please contact your insurance provider to confirm that Main Street Family Clinic is in network for your specific plan. Call us at 580-886-1400 with questions.

Cash Pay / Self-Pay Options

Cash prices available for uninsured patients
or those who prefer to skip their deductible.

Office Visits

Returning patients
$100
New patients
$150

Department of Transportation (DOT) Physical Exams

Visit & Lab
$100

These prices apply to standard office visits. Additional procedures or testing may have separate charges. For details, please ask when scheduling.

Payments can be made in office, online, or over the phone. To make a payment, call us at 580-886-1400 or use our secure payment portal below.

Payment Portal
Founder’s Note
“It is my primary goal to make everyone feel welcome,
take care of their physical and emotional needs,
and help them live quality lives.”

Beth Holderby Acre, APRN-CNP, RN, MSN, BS, ADN
Lead Medical Provider & Founder

Now Accepting New Patients!

Join the Main Street Family by calling today or coming in
to schedule your appointment with us!

Visit Main Street Family Clinic

Hours

Tuesday
8:00 am – 5:00 pm
Wednesday
8:00 am – 5:00 pm
Thursday
8:00 am – 5:00 pm
Friday
8:00 am – 5:00 pm